Dust and biomass burning aerosols play a key role in the Earth’s energy and nutrition budget, influencing global and regional environment. The variations in dust and wildfire activities, namely the emission/activation, transport/spread, and deposition/termination processes, are largely driven by variations in regional climate and anthropogenic activity. Deeper understanding on the human-climate-dust/wildfires will aid successful prediction and projection of changes in dust/wildfire activities and their environmental influences. In this presentation, I will cover my research on the human-climate-dust/wildfire interactions based on satellite observations and statistical or dynamical modeling approaches.